Also known as: SMA; F-Actin
Smooth muscle auto-antibodies are associated with autoimmune chronic active hepatitis (CAH). The major auto-antigen being F-Actin. IgG smooth muscle antibodies to F-Actin are present at high titre in about 70% of autoimmune active chronic hepatitis (non hepatitis B/C) and in approximately 25 - 50% of patients with primary biliary cirrhosis. These antibodies often occur as a 'false positive' in patients with viral infections.
Specimen requirements
Serum 1ml
Cost
Price on application
Laboratory turnaround time
5 days
Laboratory method
Indirect Immunofluorescence
Reference range/units
Positive or Negative with a titre
Associated tests
Part of Autoantibody screen
Sample stability
2 months at 2-8ºC
Shipping and storage
UK and Ireland
Ambient temperature and first class post. Hays DX users please enquire via email below.
International
Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.
Ensure delivery Monday to Friday 09:00 - 17:30.
Further information and contact details
For further information, email immunologylab.enquiries@ouh.nhs.uk
