Also known as: Alpha3; AChR; α3AChR
Ganglionic (alpha3) acetylcholine receptor antibodies have been reported in the sera of some patients with autoimmune autonomic neuropathy. Their frequency is not yet known. They may also be found in patients with paraneoplastic disorders particularly in association with small cell lung carcinoma (SCLC) or thymoma. Their presence suggests an immunotherapy-responsive condition - Vernino S. et al., NEJM 2000:343 847-855
Specimen requirements
Serum 1ml; CSF not suitable for testing.
Cost
50 UKP - UK NHS, International and Private
Laboratory turnaround time
42 days
Laboratory method
Radioimmunoassay (RIA)
Reference range/units
Not applicable
Associated tests
Not applicable
Sample stability
4 months at 2-8ºC
Shipping and storage
UK and Ireland
Ambient temperature and first class post. Hays DX users please enquire via email below.
International
Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.
Ensure delivery Monday to Friday 09:00 - 17:30.
UKAS Accreditation status
This test is not UKAS Accredited as it is performed by the University of Oxford Neuroimmunology Research Group.
Further information and contact details
For further information, email immunologylab.enquiries@ouh.nhs.uk